There are many different types of insomnia, but it’s often assessed in two broad categories, primary and secondary. Insomnia is a sleep disorder that can make it hard for people to fall asleep or stay asleep. It’s through this mechanism that trazodone can help with some cases of depression.īefore we move on to examine the side effects of using trazodone for sleep, what is insomnia? We’ll briefly highlight that right now. Oleptro is the only remaining brand name for trazodone. Categorized as a SARI ( serotonin antagonist reuptake inhibitor), trazodone stops neurons from reabsorbing serotonin once the neurotransmitter has been released into the CNS. So, although not designed as a sedative or hypnotic to address sleep disorders, doctors are now prescribing trazodone off-label to mitigate insomnia.įirst approved by the FDA in 1981 (under the brand name Desyrel), trazodone is now available as a generic medication produced by several leading drug companies. Many other antidepressants are more effective at treating depression, while the chemical composition of trazodone gives it mild sedating properties, often unwanted if being used to treat depression. Because of its effects on serotonin, trazodone functions well as a sleep aid. These drugs work by moderating levels of serotonin – a neurotransmitter – in the brain and increasing its availability in the CNS (central nervous system). The antidepressant belongs to a class of medications called serotonin modulators.
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